CATH Classification

Domain Context

CATH Clusters

Superfamily Coagulation Factor IX
Functional Family vitamin K-dependent protein S

Enzyme Information

3.4.21.22
Coagulation factor IXa.
based on mapping to UniProt P00740
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
-!- The proenzyme factor IX is activated by EC 3.4.21.27. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P00740
FA9_HUMAN
Homo sapiens
Coagulation factor IX

PDB Structure

PDB 1CFH
External Links
Method SOLUTION NMR
Organism
Primary Citation
Structure of the metal-free gamma-carboxyglutamic acid-rich membrane binding region of factor IX by two-dimensional NMR spectroscopy.
Freedman, S.J., Furie, B.C., Furie, B., Baleja, J.D.
J.Biol.Chem.