CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Cationic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00760
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P00760
TRY1_BOVIN
Bos taurus
Cationic trypsin

PDB Structure

PDB 1C5S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator.
Katz, B.A., Mackman, R., Luong, C., Radika, K., Martelli, A., Sprengeler, P.A., Wang, J., Chan, H., Wong, L.
Chem.Biol.