CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.170 | Formyl transferase, N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Formyl transferase, N-terminal domain |
| Functional Family | Phosphoribosylglycinamide formyltransferase |
Enzyme Information
| 2.1.2.2 |
Phosphoribosylglycinamide formyltransferase.
based on mapping to UniProt P08179
10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
|
UniProtKB Entries (1)
| P08179 |
PUR3_ECOLI
Escherichia coli K-12
Phosphoribosylglycinamide formyltransferase
|
PDB Structure
| PDB | 1C2T |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid.
Biochemistry
|