CATH Classification

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family p-hydroxybenzoate hydroxylase

Enzyme Information

1.14.13.2
4-hydroxybenzoate 3-monooxygenase.
based on mapping to UniProt P00438
4-hydroxybenzoate + NADPH + O(2) = protocatechuate + NADP(+) + H(2)O.
-!- Most enzymes from Pseudomonas are highly specific for NAD(P)H (cf. EC 1.14.13.33).

UniProtKB Entries (1)

P00438
PHHY_PSEFL
Pseudomonas fluorescens
P-hydroxybenzoate hydroxylase

PDB Structure

PDB 1BGN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Interdomain binding of NADPH in p-hydroxybenzoate hydroxylase as suggested by kinetic, crystallographic and modeling studies of histidine 162 and arginine 269 variants.
Eppink, M.H., Schreuder, H.A., van Berkel, W.J.
J.Biol.Chem.