CATH Domain 1b50A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.50	OB fold (Dihydrolipoamide Acetyltransferase, E2P)
	2.40.50.40

Domain Context

CATH Clusters

Superfamily	2.40.50.40
Functional Family	C-C motif chemokine

Enzyme Information

UniProtKB Entries (1)

CCL3_HUMAN

Homo sapiens

C-C motif chemokine 3

PDB Structure

PDB	1B50
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Pichia
Primary Citation	Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants. Czaplewski, L.G., McKeating, J., Craven, C.J., Higgins, L.D., Appay, V., Brown, A., Dudgeon, T., Howard, L.A., Meyers, T., Owen, J., Palan, S.R., Tan, P., Wilson, G., Woods, N.R., Heyworth, C.M., Lord, B.I., Brotherton, D., Christison, R., Craig, S., Cribbes, S., Edwards, R.M., Evans, S.J., Gilbert, R., Morgan, P., Randle, E., Schofield, N., Varley, P.G., Fisher, J., Waltho, J.P., Hunter, M.G. J.Biol.Chem.