CATH Classification

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 1
Functional Family Aldehyde dehydrogenase family (Eurofung)

Enzyme Information

1.2.1.3
Aldehyde dehydrogenase (NAD(+)).
based on mapping to UniProt P20000
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
-!- Wide specificity, including oxidation of D-glucuronolactone to D-glucarate. -!- Formerly EC 1.1.1.70.

UniProtKB Entries (1)

P20000
ALDH2_BOVIN
Bos taurus
Aldehyde dehydrogenase, mitochondrial

PDB Structure

PDB 1AG8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion.
Steinmetz, C.G., Xie, P., Weiner, H., Hurley, T.D.
Structure