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CATH Superfamily 3.40.50.12550

Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2

The adenylation domains composed of two MoeB/ThiF-homology motifs (hereafter, IAD and AAD, for 'inactive' and 'active' adenylation domain, respectively), the latter of which binds ATP and Ub.

DOI:10.1016/j.molcel.2013.01.013

GO Diversity

Unique GO annotations
58 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
1492 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 19
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 1
Unique PDBs: 10
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 17
Function
Unique EC: 1
Unique GO: 58
Taxonomy
Unique Species: 1492