The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"RepB DNA-primase, N-terminal domain
".
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Primases are necessary for phage replication. RepBprime primases such as in this family recognise both ssiA and ssiB, ie only 1 single-stranded primase initiation site on each strand, independently of each other and then synthesise primers that are elongated by DNA polymerase III. The phage is thus replicated exclusively in leading strand mode PFAM:PF16793.
RepB has a dumbbell shaped and comprises two domains: an N-terminal catalytic domain (composed of 2 antiparallel beta-sheets flanked by 6 alpha-helices) separated by a long alpha-helix plus tether and a C-terminal helical-bundle domain (made up of 5 helices) DOI:10.1073/pnas.0902910106.
| Structures | |
|---|---|
| Domains: | 1 |
| Domain clusters (>95% seq id): | 1 |
| Domain clusters (>35% seq id): | 1 |
| Unique PDBs: | 1 |
| Alignments | |
| Structural Clusters (5A): | 1 |
| Structural Clusters (9A): | 1 |
| FunFam Clusters: | 0 |
| Function | |
| Unique EC: | 1 |
| Unique GO: | |
| Taxonomy | |
| Unique Species: | 574 |