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CATH Superfamily 1.20.120.1270

CagA exotoxin domain III

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CagA exotoxin domain III
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: CagA exotoxin domain III

The Helicobacter pylori bacterial virulence determinant CagA (cytotoxin-associated gene A) protein is a cell-surface antigen which plays a role in recruiting host proteins to potentiate oncogenic signalling. The structure of CagA comprises three domains. This superfamily includes the C-terminal Domain III helical bundle. INTERPRO:IPR005169,DOI:10.1016/j.chom.2012.05.010

GO Diversity

Unique GO annotations
1 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
30 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 3
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 3
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO: 1
Taxonomy
Unique Species: 30