PDB 5x1w

PDB Information

PDB5X1W
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator
Matsui, Y., Yasumatsu, I., Asahi, T., Kitamura, T., Kanai, K., Ubukata, O., Hayasaka, H., Takaishi, S., Hanzawa, H., Katakura, S.
Bioorg. Med. Chem.
HeaderTransferase
Released2017-01-27
Resolution3.000
CATH Insert Date14 Nov, 2017

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5x1wA01 10 Dec, 2017 3.40.1380.20 Assigned
5x1wA02 10 Dec, 2017 3.20.20.60 Assigned
5x1wA03 10 Dec, 2017 Holding pen
5x1wB01 10 Dec, 2017 3.40.1380.20 Assigned
5x1wB02 10 Dec, 2017 3.20.20.60 Assigned
5x1wB03 10 Dec, 2017 Holding pen
5x1wC01 10 Dec, 2017 3.40.1380.20 Assigned
5x1wC02 10 Dec, 2017 3.20.20.60 Assigned
5x1wC03 10 Dec, 2017 Holding pen
5x1wD01 10 Dec, 2017 3.40.1380.20 Assigned
5x1wD02 10 Dec, 2017 3.20.20.60 Assigned
5x1wD03 10 Dec, 2017 Holding pen

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM