PDB Information

PDB5WZZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli K-12
Gene SourceHomo sapiens
Primary Citation
The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
Ji, L., Jiang, B., Jiang, X., Charlat, O., Chen, A., Mickanin, C., Bauer, A., Xu, W., Yan, X.-X., Cong, F.
Genes Dev.
HeaderLigase
Released2017-01-19
Resolution2.100
CATH Insert Date14 Nov, 2017

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Rejected
F 14 Nov, 2017 Rejected
G 14 Nov, 2017 Rejected
H 14 Nov, 2017 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5wzzA01 10 Dec, 2017 3.30.40.10 Assigned
5wzzA02 10 Dec, 2017 2.60.210.10 Assigned
5wzzB01 10 Dec, 2017 3.30.40.10 Assigned
5wzzB02 10 Dec, 2017 2.60.210.10 Assigned
5wzzC01 10 Dec, 2017 3.30.40.10 Assigned
5wzzC02 10 Dec, 2017 2.60.210.10 Assigned
5wzzD01 10 Dec, 2017 3.30.40.10 Assigned
5wzzD02 10 Dec, 2017 2.60.210.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
O15169 AXIN1_HUMAN Homo sapiens Axin-1
Q8IUQ4 SIAH1_HUMAN Homo sapiens E3 ubiquitin-protein ligase SIAH1
O15169 AXIN1_HUMAN Homo sapiens Axin-1
Q8IUQ4 SIAH1_HUMAN Homo sapiens E3 ubiquitin-protein ligase SIAH1
Q8IUQ4 SIAH1_HUMAN Homo sapiens E3 ubiquitin-protein ligase SIAH1
Q8IUQ4 SIAH1_HUMAN Homo sapiens E3 ubiquitin-protein ligase SIAH1
O15169 AXIN1_HUMAN Homo sapiens Axin-1
O15169 AXIN1_HUMAN Homo sapiens Axin-1