PDB Information

PDB5TSW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity.
Cha, S.S., Kim, J.S., Cho, H.S., Shin, N.K., Jeong, W., Shin, H.C., Kim, Y.J., Hahn, J.H., Oh, B.H.
J.Biol.Chem.
HeaderLymphokine
Released1999-04-22
Resolution2.5
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
E 05 Mar, 2006 Chopped
F 05 Mar, 2006 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5tswA00 05 Mar, 2006 2.60.120.40 Assigned
5tswB00 05 Mar, 2006 2.60.120.40 Assigned
5tswC00 05 Mar, 2006 2.60.120.40 Assigned
5tswD00 05 Mar, 2006 2.60.120.40 Assigned
5tswE00 05 Mar, 2006 2.60.120.40 Assigned
5tswF00 05 Mar, 2006 2.60.120.40 Assigned

Uniprot Entries (6)

Accession Gene ID Taxon Description
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin