PDB 5npk

PDB Information

PDB5NPK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus
Primary Citation
Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase.
Chan, P.F., Germe, T., Bax, B.D., Huang, J., Thalji, R.K., Bacque, E., Checchia, A., Chen, D., Cui, H., Ding, X., Ingraham, K., McCloskey, L., Raha, K., Srikannathasan, V., Maxwell, A., Stavenger, R.A.
Proc. Natl. Acad. Sci. U.S.A.
HeaderIsomerase
Released2017-04-17
Resolution1.980
CATH Insert Date14 Nov, 2017

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
b 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
d 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
e 14 Nov, 2017 Rejected
E 14 Nov, 2017 Rejected
f 14 Nov, 2017 Rejected
F 14 Nov, 2017 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5npkb01 10 Dec, 2017 Holding pen
5npkB01 10 Dec, 2017 Holding pen
5npkb02 10 Dec, 2017 Holding pen
5npkB02 10 Dec, 2017 Holding pen
5npkd01 10 Dec, 2017 Holding pen
5npkD01 10 Dec, 2017 Holding pen
5npkd02 10 Dec, 2017 Holding pen
5npkD02 10 Dec, 2017 Holding pen

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B