PDB Information

PDB5L62
MethodX-RAY DIFFRACTION
Host OrganismSaccharomyces cerevisiae S288c
Gene SourceHomo sapiens
Primary Citation
A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
Huber, E.M., Heinemeyer, W., de Bruin, G., Overkleeft, H.S., Groll, M.
EMBO J.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-05-28
Resolution2.800
CATH Insert Date25 Dec, 2016

PDB Images (57)

PDB Prints

PDB Chains (28)

Chain ID Date inserted into CATH CATH Status
a 26 Dec, 2016 Chopped
A 26 Dec, 2016 Chopped
b 26 Dec, 2016 Chopped
B 26 Dec, 2016 Chopped
C 26 Dec, 2016 Chopped
D 26 Dec, 2016 Chopped
E 26 Dec, 2016 Chopped
F 26 Dec, 2016 Chopped
G 26 Dec, 2016 Chopped
H 26 Dec, 2016 Chopped
I 26 Dec, 2016 Chopped
J 26 Dec, 2016 Chopped
K 26 Dec, 2016 Chopped
L 26 Dec, 2016 Chopped
M 26 Dec, 2016 Chopped
N 26 Dec, 2016 Chopped
O 26 Dec, 2016 Chopped
P 26 Dec, 2016 Chopped
Q 26 Dec, 2016 Chopped
R 26 Dec, 2016 Chopped
S 26 Dec, 2016 Chopped
T 26 Dec, 2016 Chopped
U 26 Dec, 2016 Chopped
V 26 Dec, 2016 Chopped
W 26 Dec, 2016 Chopped
X 26 Dec, 2016 Chopped
Y 26 Dec, 2016 Chopped
Z 26 Dec, 2016 Chopped

CATH Domains (28)

Domain ID Date inserted into CATH Superfamily CATH Status
5l62a00 30 Dec, 2016 3.60.20.10 Assigned
5l62A00 30 Dec, 2016 3.60.20.10 Assigned
5l62b00 30 Dec, 2016 3.60.20.10 Assigned
5l62B00 30 Dec, 2016 3.60.20.10 Assigned
5l62C00 30 Dec, 2016 3.60.20.10 Assigned
5l62D00 30 Dec, 2016 3.60.20.10 Assigned
5l62E00 30 Dec, 2016 3.60.20.10 Assigned
5l62F00 30 Dec, 2016 3.60.20.10 Assigned
5l62G00 30 Dec, 2016 3.60.20.10 Assigned
5l62H00 30 Dec, 2016 3.60.20.10 Assigned
5l62I00 30 Dec, 2016 3.60.20.10 Assigned
5l62J00 30 Dec, 2016 3.60.20.10 Assigned
5l62K00 30 Dec, 2016 3.60.20.10 Assigned
5l62L00 30 Dec, 2016 3.60.20.10 Assigned
5l62M00 30 Dec, 2016 3.60.20.10 Assigned
5l62N00 30 Dec, 2016 3.60.20.10 Assigned
5l62O00 30 Dec, 2016 3.60.20.10 Assigned
5l62P00 30 Dec, 2016 3.60.20.10 Assigned
5l62Q00 30 Dec, 2016 3.60.20.10 Assigned
5l62R00 30 Dec, 2016 3.60.20.10 Assigned
5l62S00 30 Dec, 2016 3.60.20.10 Assigned
5l62T00 30 Dec, 2016 3.60.20.10 Assigned
5l62U00 30 Dec, 2016 3.60.20.10 Assigned
5l62V00 30 Dec, 2016 3.60.20.10 Assigned
5l62W00 30 Dec, 2016 3.60.20.10 Assigned
5l62X00 30 Dec, 2016 3.60.20.10 Assigned
5l62Y00 30 Dec, 2016 3.60.20.10 Assigned
5l62Z00 30 Dec, 2016 3.60.20.10 Assigned

UniProtKB Entries (32)

Accession Gene ID Taxon Description
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P28074 PSB5_HUMAN Homo sapiens Proteasome subunit beta type-5
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P20618 PSB1_HUMAN Homo sapiens Proteasome subunit beta type-1
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P28074 PSB5_HUMAN Homo sapiens Proteasome subunit beta type-5
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P20618 PSB1_HUMAN Homo sapiens Proteasome subunit beta type-1
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5