PDB Information

PDB5L3G
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Speranzini, V., Rotili, D., Ciossani, G., Pilotto, S., Marrocco, B., Forgione, M., Lucidi, A., Forneris, F., Mehdipour, P., Velankar, S., Mai, A., Mattevi, A.
Sci Adv
HeaderOxidoreductase/Repressor
Released2016-04-10
Resolution3.100
CATH Insert Date09 Oct, 2016

PDB Images (8)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 10 Oct, 2016 Chopped
B 10 Oct, 2016 Chopped
C 10 Oct, 2016 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5l3gA01 13 Oct, 2016 1.10.10.10 Assigned
5l3gA02 13 Oct, 2016 Holding pen
5l3gA03 13 Oct, 2016 1.10.287.80 Assigned
5l3gB00 14 Oct, 2016 1.20.58.1880 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60341 KDM1A_HUMAN Homo sapiens Lysine-specific histone demethylase 1A
Q9UKL0 RCOR1_HUMAN Homo sapiens REST corepressor 1