PDB Information

PDB5K14
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 group M subtype B (isolate HXB2)
Primary Citation
Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl)methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1.
Simon, P., Baszczynski, O., Saman, D., Stepan, G., Hu, E., Lansdon, E.B., Jansa, P., Janeba, Z.
Eur.J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-05-17
Resolution2.400
CATH Insert Date10 Jul, 2016

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Jul, 2016 Chopped
B 11 Jul, 2016 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
5k14A01 20 Jul, 2016 3.10.10.10 Assigned
5k14A02 20 Jul, 2016 3.30.70.270 Assigned
5k14A03 20 Jul, 2016 3.30.70.270 Assigned
5k14A04 20 Jul, 2016 3.30.70.270 Assigned
5k14A05 20 Jul, 2016 3.30.420.10 Assigned
5k14B01 20 Jul, 2016 3.10.10.10 Assigned
5k14B02 20 Jul, 2016 3.30.70.270 Assigned
5k14B03 20 Jul, 2016 3.30.70.270 Assigned
5k14B04 20 Jul, 2016 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein
P0C6F2 POL_HV1LW Human immunodeficiency virus type 1 lw12.3 isolate Gag-Pol polyprotein