PDB Information

PDB5IN5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-Dehydratase.
Allen, J.G., Mujacic, M., Frohn, M.J., Pickrell, A.J., Kodama, P., Bagal, D., San Miguel, T., Sickmier, E.A., Osgood, S., Swietlow, A., Li, V., Jordan, J.B., Kim, K.W., Rousseau, A.C., Kim, Y.J., Caille, S., Achmatowicz, M., Thiel, O., Fotsch, C.H., Reddy, P., McCarter, J.D.
Acs Chem.Biol.
HeaderLyase/Inhibitor
Released2016-03-07
Resolution1.900
CATH Insert Date04 Sep, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2016 Chopped
B 05 Sep, 2016 Chopped
C 05 Sep, 2016 Chopped
D 05 Sep, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5in5A01 09 Sep, 2016 3.40.50.720 Assigned
5in5A02 09 Sep, 2016 3.90.25.10 Assigned
5in5B01 09 Sep, 2016 3.40.50.720 Assigned
5in5B02 09 Sep, 2016 3.90.25.10 Assigned
5in5C01 09 Sep, 2016 3.40.50.720 Assigned
5in5C02 09 Sep, 2016 3.90.25.10 Assigned
5in5D01 09 Sep, 2016 3.40.50.720 Assigned
5in5D02 09 Sep, 2016 3.90.25.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O60547 GMDS_HUMAN Homo sapiens GDP-mannose 4,6 dehydratase
O60547 GMDS_HUMAN Homo sapiens GDP-mannose 4,6 dehydratase
O60547 GMDS_HUMAN Homo sapiens GDP-mannose 4,6 dehydratase
O60547 GMDS_HUMAN Homo sapiens GDP-mannose 4,6 dehydratase