PDB 5gwi
PDB Information
| PDB | 5GWI |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21(DE3) |
| Gene Source | Homo sapiens |
| Primary Citation | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res.
|
| Header | Isomerase/Dna/Isomerase Inhibitor |
| Released | 2016-09-12 |
| Resolution | 2.740 |
| CATH Insert Date | 14 Nov, 2017 |
PDB Images (15)
5gwi
PDB 5gwi
5gwiA
PDB Chain 5gwiA
5gwiB
PDB Chain 5gwiB
5gwiC
PDB Chain 5gwiC
5gwiD
PDB Chain 5gwiD
5gwiE
PDB Chain 5gwiE
5gwiF
PDB Chain 5gwiF
5gwiA01
CATH Domain 5gwiA01
5gwiA02
CATH Domain 5gwiA02
5gwiA03
CATH Domain 5gwiA03
5gwiA04
CATH Domain 5gwiA04
5gwiB01
CATH Domain 5gwiB01
5gwiB02
CATH Domain 5gwiB02
5gwiB03
CATH Domain 5gwiB03
5gwiB04
CATH Domain 5gwiB04
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 14 Nov, 2017 | Chopped |
| B | 14 Nov, 2017 | Chopped |
| C | 14 Nov, 2017 | Rejected |
| D | 14 Nov, 2017 | Rejected |
| E | 14 Nov, 2017 | Rejected |
| F | 14 Nov, 2017 | Rejected |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5gwiA01 | 10 Dec, 2017 | 3.40.50.670 | Assigned |
| 5gwiA02 | 10 Dec, 2017 | 3.90.199.10 | Assigned |
| 5gwiA03 | 10 Dec, 2017 | 3.30.1360.40 | Assigned |
| 5gwiA04 | 10 Dec, 2017 | 1.10.268.10 | Assigned |
| 5gwiB01 | 10 Dec, 2017 | 3.40.50.670 | Assigned |
| 5gwiB02 | 10 Dec, 2017 | 3.90.199.10 | Assigned |
| 5gwiB03 | 10 Dec, 2017 | 3.30.1360.40 | Assigned |
| 5gwiB04 | 10 Dec, 2017 | 1.10.268.10 | Assigned |
UniProtKB Entries (2)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q02880 | TOP2B_HUMAN | Homo sapiens | DNA topoisomerase 2-beta |
| Q02880 | TOP2B_HUMAN | Homo sapiens | DNA topoisomerase 2-beta |