PDB Information

PDB5FZJ
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceMUS MUSCULUS
Primary Citation
Mono-Acidic Inhibitors of the Kelch-Like Ech-Associated Protein 1 : Nuclear Factor Erythroid 2-Related Factor 2 (Keap1:Nrf2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.
Davies, T.G., Wixted, W.E., Coyle, J.E., Griffiths-Jones, C., Hearn, K., Mcmenamin, R.L., Norton, D., Rich, S.J., Richardson, C., Saxty, G., Willems, H.M.G., Woolford, A.J., Cottom, J.E., Kou, J., Yonchuk, J.G., Feldser, H.G., Sanchez, Y., Foley, J.P., Bolognese, B.J., Logan, G.A., Podolin, P.L., Yan, H., Callahan, J.F., Heightman, T.D., Kerns, J.K.
J.Med.Chem.
HeaderTranscription
Released2016-03-14
Resolution2.010
CATH Insert Date24 Apr, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5fzjA00 12 May, 2016 2.120.10.80 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9Z2X8 KEAP1_MOUSE Mus musculus Kelch-like ECH-associated protein 1