PDB Information

PDB5EML
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
Duncan, K.W., Rioux, N., Boriack-Sjodin, P.A., Munchhof, M.J., Reiter, L.A., Majer, C.R., Jin, L., Johnston, L.D., Chan-Penebre, E., Kuplast, K.G., Porter Scott, M., Pollock, R.M., Waters, N.J., Smith, J.J., Moyer, M.P., Copeland, R.A., Chesworth, R.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2015-11-06
Resolution2.390
CATH Insert Date10 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5emlA01 09 May, 2016 3.20.20.150 Assigned
5emlA02 09 May, 2016 3.40.50.150 Assigned
5emlA03 09 May, 2016 2.70.160.11 Assigned
5emlB00 09 May, 2016 2.130.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O14744 ANM5_HUMAN Homo sapiens Protein arginine N-methyltransferase 5
Q9BQA1 MEP50_HUMAN Homo sapiens Methylosome protein 50