PDB 4zk5

PDB Links
Overview

PDB Information

PDB	4ZK5
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis. Ndubaku, C.O., Crawford, T.D., Chen, H., Boggs, J.W., Drobnick, J., Harris, S.F., Jesudason, R., McNamara, E., Nonomiya, J., Sambrone, A., Schmidt, S., Smyczek, T., Vitorino, P., Wang, L., Wu, P., Yeung, S., Chen, J., Chen, K., Ding, C.Z., Wang, T., Xu, Z., Gould, S.E., Murray, L.J., Ye, W. Acs Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2015-04-29
Resolution	2.890
CATH Insert Date	20 Sep, 2015

PDB Images (7)

Image of CATH 4zk5

4zk5

PDB 4zk5

Image of CATH 4zk5A

4zk5A

PDB Chain 4zk5A

Image of CATH 4zk5B

4zk5B

PDB Chain 4zk5B

Image of CATH 4zk5A01

4zk5A01

CATH Domain 4zk5A01

Image of CATH 4zk5A02

4zk5A02

CATH Domain 4zk5A02

Image of CATH 4zk5B01

4zk5B01

CATH Domain 4zk5B01

Image of CATH 4zk5B02

4zk5B02

CATH Domain 4zk5B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	21 Sep, 2015	Chopped
B	21 Sep, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zk5A01	30 Sep, 2015	3.30.200.20	Assigned
4zk5A02	30 Sep, 2015	1.10.510.10	Assigned
4zk5B01	30 Sep, 2015	3.30.200.20	Assigned
4zk5B02	30 Sep, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O95819	M4K4_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 4
O95819	M4K4_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 4