PDB 4x8s

PDB Information

PDB4X8S
MethodX-RAY DIFFRACTION
Host OrganismCricetinae
Gene SourceHomo sapiens
Primary Citation
Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening.
Cheney, D.L., Bozarth, J.M., Metzler, W.J., Morin, P.E., Mueller, L., Newitt, J.A., Nirschl, A.H., Rendina, A.R., Tamura, J.K., Wei, A., Wen, X., Wurtz, N.R., Seiffert, D.A., Wexler, R.R., Priestley, E.S.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-12-10
Resolution2.100
CATH Insert Date28 Jun, 2015

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
H 29 Jun, 2015 Chopped
L 29 Jun, 2015 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4x8sH01 22 Jul, 2015 2.40.10.10 Assigned
4x8sH02 22 Jul, 2015 2.40.10.10 Assigned
4x8sL00 20 Jul, 2015 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII