PDB 4x1y

PDB Information

PDB4X1Y
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications.
Maderna, A., Doroski, M., Subramanyam, C., Porte, A., Leverett, C.A., Vetelino, B.C., Chen, Z., Risley, H., Parris, K., Pandit, J., Varghese, A.H., Shanker, S., Song, C., Sukuru, S.C., Farley, K.A., Wagenaar, M.M., Shapiro, M.J., Musto, S., Lam, M.H., Loganzo, F., O'Donnell, C.J.
J.Med.Chem.
HeaderStructural Protein/Inhibitor
Released2014-11-25
Resolution3.190
CATH Insert Date28 Jun, 2015

PDB Images (19)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped
E 29 Jun, 2015 Chopped

CATH Domains (13)

Domain ID Date inserted into CATH Superfamily CATH Status
4x1yA01 22 Jul, 2015 3.40.50.1440 Assigned
4x1yA02 22 Jul, 2015 3.30.1330.20 Assigned
4x1yA03 22 Jul, 2015 1.10.287.600 Assigned
4x1yB01 22 Jul, 2015 3.40.50.1440 Assigned
4x1yB02 22 Jul, 2015 3.30.1330.20 Assigned
4x1yB03 22 Jul, 2015 1.10.287.600 Assigned
4x1yC01 22 Jul, 2015 3.40.50.1440 Assigned
4x1yC02 22 Jul, 2015 3.30.1330.20 Assigned
4x1yC03 22 Jul, 2015 1.10.287.600 Assigned
4x1yD01 22 Jul, 2015 3.40.50.1440 Assigned
4x1yD02 22 Jul, 2015 3.30.1330.20 Assigned
4x1yD03 22 Jul, 2015 1.10.287.600 Assigned
4x1yE01 22 Jul, 2015 6.10.280.30 Assigned

UniProtKB Entries (5)

Accession Gene ID Taxon Description
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
D0VWZ0 D0VWZ0_SHEEP Ovis aries Tubulin alpha chain
D0VWY9 D0VWY9_SHEEP Ovis aries Tubulin beta chain
D0VWZ0 D0VWZ0_SHEEP Ovis aries Tubulin alpha chain
D0VWY9 D0VWY9_SHEEP Ovis aries Tubulin beta chain