PDB 4rfm

PDB Information

PDB4RFM
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo.
Burch, J.D., Barrett, K., Chen, Y., DeVoss, J., Eigenbrot, C., Goldsmith, R., Ismaili, M.H., Lau, K., Lin, Z., Ortwine, D.F., Zarrin, A.A., McEwan, P.A., Barker, J.J., Ellebrandt, C., Kordt, D., Stein, D.B., Wang, X., Chen, Y., Hu, B., Xu, X., Yuen, P.W., Zhang, Y., Pei, Z.
J.Med.Chem.
HeaderTransferase/Inhibitor
Released2014-09-26
Resolution2.100
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4rfmA01 10 Jul, 2015 3.30.200.20 Assigned
4rfmA02 10 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK