PDB 4r76

PDB Links
Overview

PDB Information

PDB	4R76
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Plasmodium falciparum fcb1/columbia
Primary Citation	Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors. Mistry, S.N., Drinkwater, N., Ruggeri, C., Sivaraman, K.K., Loganathan, S., Fletcher, S., Drag, M., Paiardini, A., Avery, V.M., Scammells, P.J., McGowan, S. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-08-27
Resolution	2.500
CATH Insert Date	09 Nov, 2014

PDB Images (37)

4r76

PDB 4r76

4r76A

PDB Chain 4r76A

4r76B

PDB Chain 4r76B

4r76C

PDB Chain 4r76C

4r76D

PDB Chain 4r76D

4r76E

PDB Chain 4r76E

4r76F

PDB Chain 4r76F

4r76G

PDB Chain 4r76G

4r76H

PDB Chain 4r76H

4r76I

PDB Chain 4r76I

4r76J

PDB Chain 4r76J

4r76K

PDB Chain 4r76K

4r76L

PDB Chain 4r76L

4r76A01

CATH Domain 4r76A01

4r76A02

CATH Domain 4r76A02

4r76B01

CATH Domain 4r76B01

4r76B02

CATH Domain 4r76B02

4r76C01

CATH Domain 4r76C01

4r76C02

CATH Domain 4r76C02

4r76D01

CATH Domain 4r76D01

4r76D02

CATH Domain 4r76D02

4r76E01

CATH Domain 4r76E01

4r76E02

CATH Domain 4r76E02

4r76F01

CATH Domain 4r76F01

4r76F02

CATH Domain 4r76F02

4r76G01

CATH Domain 4r76G01

4r76G02

CATH Domain 4r76G02

4r76H01

CATH Domain 4r76H01

4r76H02

CATH Domain 4r76H02

4r76I01

CATH Domain 4r76I01

4r76I02

CATH Domain 4r76I02

4r76J01

CATH Domain 4r76J01

4r76J02

CATH Domain 4r76J02

4r76K01

CATH Domain 4r76K01

4r76K02

CATH Domain 4r76K02

4r76L01

CATH Domain 4r76L01

4r76L02

CATH Domain 4r76L02

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	10 Nov, 2014	Chopped
B	10 Nov, 2014	Chopped
C	10 Nov, 2014	Chopped
D	10 Nov, 2014	Chopped
E	10 Nov, 2014	Chopped
F	10 Nov, 2014	Chopped
G	10 Nov, 2014	Chopped
H	10 Nov, 2014	Chopped
I	10 Nov, 2014	Chopped
J	10 Nov, 2014	Chopped
K	10 Nov, 2014	Chopped
L	10 Nov, 2014	Chopped

CATH Domains (24)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4r76A01	14 Nov, 2014	3.40.220.10	Assigned
4r76A02	14 Nov, 2014	3.40.630.10	Assigned
4r76B01	14 Nov, 2014	3.40.220.10	Assigned
4r76B02	14 Nov, 2014	3.40.630.10	Assigned
4r76C01	14 Nov, 2014	3.40.220.10	Assigned
4r76C02	14 Nov, 2014	3.40.630.10	Assigned
4r76D01	14 Nov, 2014	3.40.220.10	Assigned
4r76D02	14 Nov, 2014	3.40.630.10	Assigned
4r76E01	14 Nov, 2014	3.40.220.10	Assigned
4r76E02	14 Nov, 2014	3.40.630.10	Assigned
4r76F01	14 Nov, 2014	3.40.220.10	Assigned
4r76F02	14 Nov, 2014	3.40.630.10	Assigned
4r76G01	14 Nov, 2014	3.40.220.10	Assigned
4r76G02	14 Nov, 2014	3.40.630.10	Assigned
4r76H01	14 Nov, 2014	3.40.220.10	Assigned
4r76H02	14 Nov, 2014	3.40.630.10	Assigned
4r76I01	14 Nov, 2014	3.40.220.10	Assigned
4r76I02	14 Nov, 2014	3.40.630.10	Assigned
4r76J01	14 Nov, 2014	3.40.220.10	Assigned
4r76J02	14 Nov, 2014	3.40.630.10	Assigned
4r76K01	14 Nov, 2014	3.40.220.10	Assigned
4r76K02	14 Nov, 2014	3.40.630.10	Assigned
4r76L01	14 Nov, 2014	3.40.220.10	Assigned
4r76L02	14 Nov, 2014	3.40.630.10	Assigned

UniProtKB Entries (12)

Accession	Gene ID	Taxon	Description
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase