PDB 4r17

PDB Links
Overview

PDB Information

PDB	4R17
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Selective inhibition of the immunoproteasome by ligand-induced crosslinking of the active site. Dubiella, C., Cui, H., Gersch, M., Brouwer, A.J., Sieber, S.A., Kruger, A., Liskamp, R.M., Groll, M. Angew.Chem.Int.Ed.Engl.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-08-04
Resolution	2.100
CATH Insert Date	26 Oct, 2014

PDB Images (57)

4r17

PDB 4r17

4r17a

PDB Chain 4r17a

4r17A

PDB Chain 4r17A

4r17b

PDB Chain 4r17b

4r17B

PDB Chain 4r17B

4r17C

PDB Chain 4r17C

4r17D

PDB Chain 4r17D

4r17E

PDB Chain 4r17E

4r17F

PDB Chain 4r17F

4r17G

PDB Chain 4r17G

4r17H

PDB Chain 4r17H

4r17I

PDB Chain 4r17I

4r17J

PDB Chain 4r17J

4r17K

PDB Chain 4r17K

4r17L

PDB Chain 4r17L

4r17M

PDB Chain 4r17M

4r17N

PDB Chain 4r17N

4r17O

PDB Chain 4r17O

4r17P

PDB Chain 4r17P

4r17Q

PDB Chain 4r17Q

4r17R

PDB Chain 4r17R

4r17S

PDB Chain 4r17S

4r17T

PDB Chain 4r17T

4r17U

PDB Chain 4r17U

4r17V

PDB Chain 4r17V

4r17W

PDB Chain 4r17W

4r17X

PDB Chain 4r17X

4r17Y

PDB Chain 4r17Y

4r17Z

PDB Chain 4r17Z

4r17a00

CATH Domain 4r17a00

4r17A00

CATH Domain 4r17A00

4r17b00

CATH Domain 4r17b00

4r17B00

CATH Domain 4r17B00

4r17C00

CATH Domain 4r17C00

4r17D00

CATH Domain 4r17D00

4r17E00

CATH Domain 4r17E00

4r17F00

CATH Domain 4r17F00

4r17G00

CATH Domain 4r17G00

4r17H00

CATH Domain 4r17H00

4r17I00

CATH Domain 4r17I00

4r17J00

CATH Domain 4r17J00

4r17K00

CATH Domain 4r17K00

4r17L00

CATH Domain 4r17L00

4r17M00

CATH Domain 4r17M00

4r17N00

CATH Domain 4r17N00

4r17O00

CATH Domain 4r17O00

4r17P00

CATH Domain 4r17P00

4r17Q00

CATH Domain 4r17Q00

4r17R00

CATH Domain 4r17R00

4r17S00

CATH Domain 4r17S00

4r17T00

CATH Domain 4r17T00

4r17U00

CATH Domain 4r17U00

4r17V00

CATH Domain 4r17V00

4r17W00

CATH Domain 4r17W00

4r17X00

CATH Domain 4r17X00

4r17Y00

CATH Domain 4r17Y00

4r17Z00

CATH Domain 4r17Z00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	27 Oct, 2014	Chopped
A	27 Oct, 2014	Chopped
b	27 Oct, 2014	Chopped
B	27 Oct, 2014	Chopped
C	27 Oct, 2014	Chopped
D	27 Oct, 2014	Chopped
E	27 Oct, 2014	Chopped
F	27 Oct, 2014	Chopped
G	27 Oct, 2014	Chopped
H	27 Oct, 2014	Chopped
I	27 Oct, 2014	Chopped
J	27 Oct, 2014	Chopped
K	27 Oct, 2014	Chopped
L	27 Oct, 2014	Chopped
M	27 Oct, 2014	Chopped
N	27 Oct, 2014	Chopped
O	27 Oct, 2014	Chopped
P	27 Oct, 2014	Chopped
Q	27 Oct, 2014	Chopped
R	27 Oct, 2014	Chopped
S	27 Oct, 2014	Chopped
T	27 Oct, 2014	Chopped
U	27 Oct, 2014	Chopped
V	27 Oct, 2014	Chopped
W	27 Oct, 2014	Chopped
X	27 Oct, 2014	Chopped
Y	27 Oct, 2014	Chopped
Z	27 Oct, 2014	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4r17a00	02 Nov, 2014	3.60.20.10	Assigned
4r17A00	02 Nov, 2014	3.60.20.10	Assigned
4r17b00	02 Nov, 2014	3.60.20.10	Assigned
4r17B00	02 Nov, 2014	3.60.20.10	Assigned
4r17C00	02 Nov, 2014	3.60.20.10	Assigned
4r17D00	02 Nov, 2014	3.60.20.10	Assigned
4r17E00	02 Nov, 2014	3.60.20.10	Assigned
4r17F00	02 Nov, 2014	3.60.20.10	Assigned
4r17G00	02 Nov, 2014	3.60.20.10	Assigned
4r17H00	02 Nov, 2014	3.60.20.10	Assigned
4r17I00	02 Nov, 2014	3.60.20.10	Assigned
4r17J00	02 Nov, 2014	3.60.20.10	Assigned
4r17K00	02 Nov, 2014	3.60.20.10	Assigned
4r17L00	02 Nov, 2014	3.60.20.10	Assigned
4r17M00	02 Nov, 2014	3.60.20.10	Assigned
4r17N00	02 Nov, 2014	3.60.20.10	Assigned
4r17O00	02 Nov, 2014	3.60.20.10	Assigned
4r17P00	02 Nov, 2014	3.60.20.10	Assigned
4r17Q00	02 Nov, 2014	3.60.20.10	Assigned
4r17R00	02 Nov, 2014	3.60.20.10	Assigned
4r17S00	02 Nov, 2014	3.60.20.10	Assigned
4r17T00	02 Nov, 2014	3.60.20.10	Assigned
4r17U00	02 Nov, 2014	3.60.20.10	Assigned
4r17V00	02 Nov, 2014	3.60.20.10	Assigned
4r17W00	02 Nov, 2014	3.60.20.10	Assigned
4r17X00	02 Nov, 2014	3.60.20.10	Assigned
4r17Y00	02 Nov, 2014	3.60.20.10	Assigned
4r17Z00	02 Nov, 2014	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5