PDB Information

PDB4OGA
MethodX-RAY DIFFRACTION
Host OrganismSACCHAROMYCES CEREVISIAE
Gene SourceHomo sapiens
Primary Citation
Protective hinge in insulin opens to enable its receptor engagement.
Menting, J.G., Yang, Y., Chan, S.J., Phillips, N.B., Smith, B.J., Whittaker, J., Wickramasinghe, N.P., Whittaker, L.J., Pandyarajan, V., Wan, Z.L., Yadav, S.P., Carroll, J.M., Strokes, N., Roberts, C.T., Ismail-Beigi, F., Milewski, W., Steiner, D.F., Chauhan, V.S., Ward, C.W., Weiss, M.A., Lawrence, M.C.
Proc.Natl.Acad.Sci.USA
HeaderHormone Receptor/Hormone/Immune System
Released2014-01-15
Resolution3.500
CATH Insert Date07 Sep, 2014

PDB Images (11)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 08 Sep, 2014 Rejected
B 08 Sep, 2014 Rejected
C 08 Sep, 2014 Chopped
D 08 Sep, 2014 Chopped
E 08 Sep, 2014 Chopped
F 08 Sep, 2014 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4ogaC00 10 Sep, 2014 2.60.40.10 Assigned
4ogaD00 10 Sep, 2014 2.60.40.10 Assigned
4ogaE01 10 Sep, 2014 3.80.20.20 Assigned
4ogaE02 10 Sep, 2014 2.10.220.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P01308 INS_HUMAN Homo sapiens Insulin
P06213 INSR_HUMAN Homo sapiens Insulin receptor
P01308 INS_HUMAN Homo sapiens Insulin
P06213 INSR_HUMAN Homo sapiens Insulin receptor