PDB 4l2y

PDB Information

PDB4L2Y
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design.
Zhao, Y., Zhang, X., Chen, Y., Lu, S., Peng, Y., Wang, X., Guo, C., Zhou, A., Zhang, J., Luo, Y., Shen, Q., Ding, J., Meng, L., Zhang, J.
ACS Med Chem Lett
HeaderSignaling Protein/Transferase/Inhibitor
Released2013-06-05
Resolution2.800
CATH Insert Date05 Jan, 2014

PDB Images (10)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Jan, 2014 Chopped
B 06 Jan, 2014 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
4l2yA01 09 Jan, 2014 3.10.20.770 Assigned
4l2yA02 09 Jan, 2014 2.60.40.150 Assigned
4l2yA03 09 Jan, 2014 1.25.40.70 Assigned
4l2yA04 09 Jan, 2014 3.30.1010.10 Assigned
4l2yA05 09 Jan, 2014 1.10.1070.11 Assigned
4l2yB01 14 Nov, 2017 Holding pen
4l2yB02 14 Nov, 2017 1.10.287.1490 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27986 P85A_HUMAN Homo sapiens Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336 PK3CA_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform