PDB 4knw

PDB Information

PDB4KNW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibitor complex.
Kim, S.H., Constantine, K.L., Duke, G.J., Goldfarb, V., Hunt, J.T., Johnson, S., Kish, K., Klei, H.E., McDonnell, P.A., Metzler, W.J., Mueller, L., Poss, M.A., Fairchild, C.R., Bhide, R.S.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2013-05-10
Resolution2.700
CATH Insert Date04 Aug, 2013

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped
B 05 Aug, 2013 Chopped
C 05 Aug, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4knwA01 14 Aug, 2013 3.40.50.1000 Assigned
4knwA02 14 Aug, 2013 1.20.120.710 Assigned
4knwB01 14 Aug, 2013 3.40.50.1000 Assigned
4knwB02 14 Aug, 2013 1.20.120.710 Assigned
4knwC01 14 Aug, 2013 3.40.50.1000 Assigned
4knwC02 14 Aug, 2013 1.20.120.710 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q8TBE9 NANP_HUMAN Homo sapiens N-acylneuraminate-9-phosphatase
Q8TBE9 NANP_HUMAN Homo sapiens N-acylneuraminate-9-phosphatase
Q8TBE9 NANP_HUMAN Homo sapiens N-acylneuraminate-9-phosphatase