PDB Information

PDB4HTZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
Zhu, J., Yang, Q., Dai, D., Huang, Q.
J.Am.Chem.Soc.
HeaderHydrolase
Released2012-11-02
Resolution2.000
CATH Insert Date15 Sep, 2013

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Sep, 2013 Chopped
B 16 Sep, 2013 Chopped
C 16 Sep, 2013 Chopped
D 16 Sep, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4htzA00 18 Sep, 2013 1.10.1300.10 Assigned
4htzB00 18 Sep, 2013 1.10.1300.10 Assigned
4htzC01 18 Sep, 2013 1.10.1300.10 Assigned
4htzD01 18 Sep, 2013 1.10.1300.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408 PDE2A_HUMAN Homo sapiens cGMP-dependent 3',5'-cyclic phosphodiesterase