PDB 4hnp

PDB Links
Overview

PDB Information

PDB	4HNP
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Trivella, D.B., Pereira, A.R., Stein, M.L., Kasai, Y., Byrum, T., Valeriote, F.A., Tantillo, D.J., Groll, M., Gerwick, W.H., Moore, B.S. Chem.Biol.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-10-20
Resolution	2.800
CATH Insert Date	02 Feb, 2014

PDB Images (57)

4hnp

PDB 4hnp

4hnpa

PDB Chain 4hnpa

4hnpA

PDB Chain 4hnpA

4hnpb

PDB Chain 4hnpb

4hnpB

PDB Chain 4hnpB

4hnpC

PDB Chain 4hnpC

4hnpD

PDB Chain 4hnpD

4hnpE

PDB Chain 4hnpE

4hnpF

PDB Chain 4hnpF

4hnpG

PDB Chain 4hnpG

4hnpH

PDB Chain 4hnpH

4hnpI

PDB Chain 4hnpI

4hnpJ

PDB Chain 4hnpJ

4hnpK

PDB Chain 4hnpK

4hnpL

PDB Chain 4hnpL

4hnpM

PDB Chain 4hnpM

4hnpN

PDB Chain 4hnpN

4hnpO

PDB Chain 4hnpO

4hnpP

PDB Chain 4hnpP

4hnpQ

PDB Chain 4hnpQ

4hnpR

PDB Chain 4hnpR

4hnpS

PDB Chain 4hnpS

4hnpT

PDB Chain 4hnpT

4hnpU

PDB Chain 4hnpU

4hnpV

PDB Chain 4hnpV

4hnpW

PDB Chain 4hnpW

4hnpX

PDB Chain 4hnpX

4hnpY

PDB Chain 4hnpY

4hnpZ

PDB Chain 4hnpZ

4hnpa00

CATH Domain 4hnpa00

4hnpA00

CATH Domain 4hnpA00

4hnpb00

CATH Domain 4hnpb00

4hnpB00

CATH Domain 4hnpB00

4hnpC00

CATH Domain 4hnpC00

4hnpD00

CATH Domain 4hnpD00

4hnpE00

CATH Domain 4hnpE00

4hnpF00

CATH Domain 4hnpF00

4hnpG00

CATH Domain 4hnpG00

4hnpH00

CATH Domain 4hnpH00

4hnpI00

CATH Domain 4hnpI00

4hnpJ00

CATH Domain 4hnpJ00

4hnpK00

CATH Domain 4hnpK00

4hnpL00

CATH Domain 4hnpL00

4hnpM00

CATH Domain 4hnpM00

4hnpN00

CATH Domain 4hnpN00

4hnpO00

CATH Domain 4hnpO00

4hnpP00

CATH Domain 4hnpP00

4hnpQ00

CATH Domain 4hnpQ00

4hnpR00

CATH Domain 4hnpR00

4hnpS00

CATH Domain 4hnpS00

4hnpT00

CATH Domain 4hnpT00

4hnpU00

CATH Domain 4hnpU00

4hnpV00

CATH Domain 4hnpV00

4hnpW00

CATH Domain 4hnpW00

4hnpX00

CATH Domain 4hnpX00

4hnpY00

CATH Domain 4hnpY00

4hnpZ00

CATH Domain 4hnpZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	03 Feb, 2014	Chopped
A	03 Feb, 2014	Chopped
b	03 Feb, 2014	Chopped
B	03 Feb, 2014	Chopped
C	03 Feb, 2014	Chopped
D	03 Feb, 2014	Chopped
E	03 Feb, 2014	Chopped
F	03 Feb, 2014	Chopped
G	03 Feb, 2014	Chopped
H	03 Feb, 2014	Chopped
I	03 Feb, 2014	Chopped
J	03 Feb, 2014	Chopped
K	03 Feb, 2014	Chopped
L	03 Feb, 2014	Chopped
M	03 Feb, 2014	Chopped
N	03 Feb, 2014	Chopped
O	03 Feb, 2014	Chopped
P	03 Feb, 2014	Chopped
Q	03 Feb, 2014	Chopped
R	03 Feb, 2014	Chopped
S	03 Feb, 2014	Chopped
T	03 Feb, 2014	Chopped
U	03 Feb, 2014	Chopped
V	03 Feb, 2014	Chopped
W	03 Feb, 2014	Chopped
X	03 Feb, 2014	Chopped
Y	03 Feb, 2014	Chopped
Z	03 Feb, 2014	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4hnpa00	07 Mar, 2014	3.60.20.10	Assigned
4hnpA00	07 Mar, 2014	3.60.20.10	Assigned
4hnpb00	07 Mar, 2014	3.60.20.10	Assigned
4hnpB00	07 Mar, 2014	3.60.20.10	Assigned
4hnpC00	07 Mar, 2014	3.60.20.10	Assigned
4hnpD00	07 Mar, 2014	3.60.20.10	Assigned
4hnpE00	07 Mar, 2014	3.60.20.10	Assigned
4hnpF00	07 Mar, 2014	3.60.20.10	Assigned
4hnpG00	07 Mar, 2014	3.60.20.10	Assigned
4hnpH00	07 Mar, 2014	3.60.20.10	Assigned
4hnpI00	07 Mar, 2014	3.60.20.10	Assigned
4hnpJ00	07 Mar, 2014	3.60.20.10	Assigned
4hnpK00	07 Mar, 2014	3.60.20.10	Assigned
4hnpL00	07 Mar, 2014	3.60.20.10	Assigned
4hnpM00	07 Mar, 2014	3.60.20.10	Assigned
4hnpN00	07 Mar, 2014	3.60.20.10	Assigned
4hnpO00	07 Mar, 2014	3.60.20.10	Assigned
4hnpP00	07 Mar, 2014	3.60.20.10	Assigned
4hnpQ00	07 Mar, 2014	3.60.20.10	Assigned
4hnpR00	07 Mar, 2014	3.60.20.10	Assigned
4hnpS00	07 Mar, 2014	3.60.20.10	Assigned
4hnpT00	07 Mar, 2014	3.60.20.10	Assigned
4hnpU00	07 Mar, 2014	3.60.20.10	Assigned
4hnpV00	07 Mar, 2014	3.60.20.10	Assigned
4hnpW00	07 Mar, 2014	3.60.20.10	Assigned
4hnpX00	07 Mar, 2014	3.60.20.10	Assigned
4hnpY00	07 Mar, 2014	3.60.20.10	Assigned
4hnpZ00	07 Mar, 2014	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5