PDB Information

PDB4HNJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
Follis, A.V., Chipuk, J.E., Fisher, J.C., Yun, M.K., Grace, C.R., Nourse, A., Baran, K., Ou, L., Min, L., White, S.W., Green, D.R., Kriwacki, R.W.
Nat.Chem.Biol.
HeaderApoptosis/Protein Binding
Released2012-10-19
Resolution2.900
CATH Insert Date27 Jan, 2013

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 28 Jan, 2013 Chopped
B 28 Jan, 2013 Chopped
C 28 Jan, 2013 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hnjA00 26 Jul, 2013 Holding pen
4hnjB00 26 Jul, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1