PDB 4hhy

PDB Information

PDB4HHY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, Synthesis, and Biological Evaluation of a Series of Benzo[de][1,7]naphthyridin-7(8H)-ones Bearing a Functionalized Longer Chain Appendage as Novel PARP1 Inhibitors.
Ye, N., Chen, C.H., Chen, T., Song, Z., He, J.X., Huan, X.J., Song, S.S., Liu, Q., Chen, Y., Ding, J., Xu, Y., Miao, Z.H., Zhang, A.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-10-10
Resolution2.360
CATH Insert Date07 Jul, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped
C 08 Jul, 2013 Chopped
D 08 Jul, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4hhyA01 13 Sep, 2013 1.20.142.10 Assigned
4hhyA02 13 Sep, 2013 3.90.228.10 Assigned
4hhyB01 13 Sep, 2013 1.20.142.10 Assigned
4hhyB02 13 Sep, 2013 3.90.228.10 Assigned
4hhyC01 13 Sep, 2013 1.20.142.10 Assigned
4hhyC02 13 Sep, 2013 3.90.228.10 Assigned
4hhyD01 13 Sep, 2013 1.20.142.10 Assigned
4hhyD02 13 Sep, 2013 3.90.228.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1