PDB 4hge

PDB Links
Overview

PDB Information

PDB	4HGE
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of potent and selective pyrazolopyrimidine janus kinase 2 inhibitors. Hanan, E.J., van Abbema, A., Barrett, K., Blair, W.S., Blaney, J., Chang, C., Eigenbrot, C., Flynn, S., Gibbons, P., Hurley, C.A., Kenny, J.R., Kulagowski, J., Lee, L., Magnuson, S.R., Morris, C., Murray, J., Pastor, R.M., Rawson, T., Siu, M., Ultsch, M., Zhou, A., Sampath, D., Lyssikatos, J.P. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2012-10-08
Resolution	2.300
CATH Insert Date	04 Nov, 2012

PDB Images (7)

Image of CATH 4hge

4hge

PDB 4hge

Image of CATH 4hgeA

4hgeA

PDB Chain 4hgeA

Image of CATH 4hgeB

4hgeB

PDB Chain 4hgeB

Image of CATH 4hgeA01

4hgeA01

CATH Domain 4hgeA01

Image of CATH 4hgeA02

4hgeA02

CATH Domain 4hgeA02

Image of CATH 4hgeB01

4hgeB01

CATH Domain 4hgeB01

Image of CATH 4hgeB02

4hgeB02

CATH Domain 4hgeB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4hgeA01	11 Nov, 2012	3.30.200.20	Assigned
4hgeA02	11 Nov, 2012	1.10.510.10	Assigned
4hgeB01	11 Nov, 2012	3.30.200.20	Assigned
4hgeB02	11 Nov, 2012	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2