PDB 4gh6

PDB Information

PDB4GH6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-Based Discovery of Highly Selective Phosphodiesterase-9A Inhibitors and Implications for Inhibitor Design.
Meng, F., Hou, J., Shao, Y.X., Wu, P.Y., Huang, M., Zhu, X., Cai, Y., Li, Z., Xu, J., Liu, P., Luo, H.B., Wan, Y., Ke, H.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-08-07
Resolution2.700
CATH Insert Date04 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4gh6A00 10 Nov, 2012 1.10.1300.10 Assigned
4gh6B00 10 Nov, 2012 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O76083 PDE9A_HUMAN Homo sapiens High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
O76083 PDE9A_HUMAN Homo sapiens High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A