PDB 4g1n

PDB Information

PDB4G1N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy.
Kung, C., Hixon, J., Choe, S., Marks, K., Gross, S., Murphy, E., Delabarre, B., Cianchetta, G., Sethumadhavan, S., Wang, X., Yan, S., Gao, Y., Fang, C., Wei, W., Jiang, F., Wang, S., Qian, K., Saunders, J., Driggers, E., Woo, H.K., Kunii, K., Murray, S., Yang, H., Yen, K., Liu, W., Cantley, L.C., Vander Heiden, M.G., Su, S.M., Jin, S., Salituro, F.G., Dang, L.
Chem.Biol.
HeaderTransferase/Activator
Released2012-07-10
Resolution2.300
CATH Insert Date04 Nov, 2012

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped
D 05 Nov, 2012 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4g1nA01 08 Feb, 2013 3.40.1380.20 Assigned
4g1nA02 08 Feb, 2013 3.20.20.60 Assigned
4g1nA03 08 Feb, 2013 2.40.33.10 Assigned
4g1nB01 08 Feb, 2013 3.40.1380.20 Assigned
4g1nB02 08 Feb, 2013 3.20.20.60 Assigned
4g1nB03 08 Feb, 2013 2.40.33.10 Assigned
4g1nC01 08 Feb, 2013 3.40.1380.20 Assigned
4g1nC02 08 Feb, 2013 3.20.20.60 Assigned
4g1nC03 08 Feb, 2013 2.40.33.10 Assigned
4g1nD01 08 Feb, 2013 3.40.1380.20 Assigned
4g1nD02 08 Feb, 2013 3.20.20.60 Assigned
4g1nD03 08 Feb, 2013 2.40.33.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM
P14618 KPYM_HUMAN Homo sapiens Pyruvate kinase PKM