PDB 4bul

PDB Links
Overview

PDB Information

PDB	4BUL
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	STAPHYLOCOCCUS AUREUS
Primary Citation	Novel Hydroxyl Tricyclics (E.G., Gsk966587) as Potent Inhibitors of Bacterial Type Iia Topoisomerases. Miles, T.J., Hennessy, A.J., Bax, B., Brooks, G., Brown, B.S., Brown, P., Cailleau, N., Chen, D., Dabbs, S., Davies, D.T., Esken, J.M., Giordano, I., Hoover, J.L., Huang, J., Jones, G.E., Kusalakumari Sukmar, S.K., Spitzfaden, C., Markwell, R.E., Minthorn, E.A., Rittenhouse, S., Gwynn, M.N., Pearson, N.D. Bioorg.Med.Chem.Lett.
Header	Isomerase
Released	2013-06-20
Resolution	2.600
CATH Insert Date	01 Sep, 2013

PDB Images (11)

Image of CATH 4bul

4bul

PDB 4bul

Image of CATH 4bulA

4bulA

PDB Chain 4bulA

Image of CATH 4bulC

4bulC

PDB Chain 4bulC

Image of CATH 4bulE

4bulE

PDB Chain 4bulE

Image of CATH 4bulF

4bulF

PDB Chain 4bulF

Image of CATH 4bulG

4bulG

PDB Chain 4bulG

Image of CATH 4bulH

4bulH

PDB Chain 4bulH

Image of CATH 4bulA01

4bulA01

CATH Domain 4bulA01

Image of CATH 4bulA02

4bulA02

CATH Domain 4bulA02

Image of CATH 4bulC01

4bulC01

CATH Domain 4bulC01

Image of CATH 4bulC02

4bulC02

CATH Domain 4bulC02

PDB Prints

PDB Chains (6)

Chain ID	Date inserted into CATH	CATH Status
A	02 Sep, 2013	Chopped
C	02 Sep, 2013	Chopped
E	02 Sep, 2013	Rejected
F	02 Sep, 2013	Rejected
G	02 Sep, 2013	Rejected
H	02 Sep, 2013	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4bulA01	13 Nov, 2013		Holding pen
4bulA02	13 Nov, 2013		Holding pen
4bulC01	13 Nov, 2013		Holding pen
4bulC02	13 Nov, 2013		Holding pen

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P66937	GYRB_STAAN	Staphylococcus aureus subsp. aureus N315	DNA gyrase subunit B
P66937	GYRB_STAAN	Staphylococcus aureus subsp. aureus N315	DNA gyrase subunit B
Q99XG5	GYRA_STAAN	Staphylococcus aureus subsp. aureus N315	DNA gyrase subunit A
Q99XG5	GYRA_STAAN	Staphylococcus aureus subsp. aureus N315	DNA gyrase subunit A