PDB 3zrc

PDB Information

PDB3ZRC
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Targeting the Von Hippel-Lindau E3 Ubiquitin Ligase Using Small Molecules to Disrupt the Vhl/Hif-1Alpha Interaction
Buckley, D.L., Van Molle, I., Gareiss, P.C., Tae, H.S., Michel, J., Noblin, D.J., Jorgensen, W.L., Ciulli, A., Crews, C.M.
J.Am.Chem.Soc.
HeaderTranscription
Released2011-06-15
Resolution2.900
CATH Insert Date27 May, 2012

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped
E 28 May, 2012 Chopped
F 28 May, 2012 Chopped
G 28 May, 2012 Chopped
H 28 May, 2012 Chopped
I 28 May, 2012 Chopped
J 28 May, 2012 Chopped
K 28 May, 2012 Chopped
L 28 May, 2012 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
3zrcA00 08 Jun, 2012 3.10.20.90 Assigned
3zrcB00 08 Jun, 2012 3.30.710.10 Assigned
3zrcC01 08 Jun, 2012 2.60.40.780 Assigned
3zrcC02 08 Jun, 2012 1.10.750.10 Assigned
3zrcD00 08 Jun, 2012 3.10.20.90 Assigned
3zrcE00 08 Jun, 2012 3.30.710.10 Assigned
3zrcF01 08 Jun, 2012 2.60.40.780 Assigned
3zrcF02 08 Jun, 2012 1.10.750.10 Assigned
3zrcG00 08 Jun, 2012 3.10.20.90 Assigned
3zrcH00 08 Jun, 2012 3.30.710.10 Assigned
3zrcI01 08 Jun, 2012 2.60.40.780 Assigned
3zrcI02 08 Jun, 2012 1.10.750.10 Assigned
3zrcJ00 08 Jun, 2012 3.10.20.90 Assigned
3zrcK00 08 Jun, 2012 3.30.710.10 Assigned
3zrcL01 08 Jun, 2012 2.60.40.780 Assigned
3zrcL02 08 Jun, 2012 1.10.750.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor