PDB Information

PDB3UWJ
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Ligand binding stepwise disrupts water network in thrombin: enthalpic and entropic changes reveal classical hydrophobic effect
Biela, A., Sielaff, F., Terwesten, F., Heine, A., Steinmetzer, T., Klebe, G.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-12-02
Resolution1.500
CATH Insert Date30 Dec, 2012

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 31 Dec, 2012 Chopped
I 31 Dec, 2012 Rejected
L 31 Dec, 2012 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3uwjH01 03 Jan, 2013 2.40.10.10 Assigned
3uwjH02 03 Jan, 2013 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P09945 HIRV2_HIRME Hirudo medicinalis Hirudin variant-2
P00734 THRB_HUMAN Homo sapiens Prothrombin