PDB 3t9t

PDB Information

PDB3T9T
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis.
Kim, K.H., Maderna, A., Schnute, M.E., Hegen, M., Mohan, S., Miyashiro, J., Lin, L., Li, E., Keegan, S., Lussier, J., Wrocklage, C., Nickerson-Nutter, C.L., Wittwer, A.J., Soutter, H., Caspers, N., Han, S., Kurumbail, R., Dunussi-Joannopoulos, K., Douhan, J., Wissner, A.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-08-03
Resolution1.650
CATH Insert Date16 Oct, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3t9tA01 01 Dec, 2011 3.30.200.20 Assigned
3t9tA02 01 Dec, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK