PDB Information

PDB3SNI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Highly Potent, Selective, and Orally Active Phosphodiesterase 10A Inhibitors.
Malamas, M.S., Ni, Y., Erdei, J., Stange, H., Schindler, R., Lankau, H.J., Grunwald, C., Fan, K.Y., Parris, K., Langen, B., Egerland, U., Hage, T., Marquis, K.L., Grauer, S., Brennan, J., Navarra, R., Graf, R., Harrison, B.L., Robichaud, A., Kronbach, T., Pangalos, M.N., Hoefgen, N., Brandon, N.J.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-06-29
Resolution1.900
CATH Insert Date30 Oct, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped
B 29 Nov, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3sniA00 08 Feb, 2013 1.10.1300.10 Assigned
3sniB00 08 Feb, 2013 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A