PDB Information

PDB3S4S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
Wang, X.X., Li, Y., Yin, Y., Mo, M., Wang, Q., Gao, W., Wang, L., Mariuzza, R.A.
Proc.Natl.Acad.Sci.USA
HeaderImmune System
Released2011-05-20
Resolution2.4
CATH Insert Date26 Sep, 2011

PDB Images (21)

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped
B 29 Nov, 2011 Chopped
C 29 Nov, 2011 Rejected
D 29 Nov, 2011 Chopped
E 29 Nov, 2011 Chopped
F 29 Nov, 2011 Rejected
G 29 Nov, 2011 Chopped
H 29 Nov, 2011 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3s4sA01 01 Dec, 2011 3.10.320.10 Assigned
3s4sA02 01 Dec, 2011 2.60.40.10 Assigned
3s4sB01 01 Dec, 2011 3.10.320.10 Assigned
3s4sB02 01 Dec, 2011 2.60.40.10 Assigned
3s4sD01 01 Dec, 2011 3.10.320.10 Assigned
3s4sD02 01 Dec, 2011 2.60.40.10 Assigned
3s4sE01 01 Dec, 2011 3.10.320.10 Assigned
3s4sE02 01 Dec, 2011 2.60.40.10 Assigned
3s4sG01 01 Dec, 2011 2.60.40.10 Assigned
3s4sG02 01 Dec, 2011 2.60.40.10 Assigned
3s4sH01 01 Dec, 2011 2.60.40.10 Assigned
3s4sH02 01 Dec, 2011 2.60.40.10 Assigned

Uniprot Entries (8)

Accession Gene ID Taxon Description
P01730 CD4_HUMAN Homo sapiens T-cell surface antigen T4/Leu-3
P01903 DRA_HUMAN Homo sapiens MHC class II antigen DRA
P04229 2B11_HUMAN Homo sapiens MHC class II antigen DRB1*1
P01730 CD4_HUMAN Homo sapiens T-cell surface antigen T4/Leu-3
P01903 DRA_HUMAN Homo sapiens MHC class II antigen DRA
P03437 HEMA_I68A0 Influenza A virus (A/Aichi/2/1968(H3N2)) Hemagglutinin
P04229 2B11_HUMAN Homo sapiens MHC class II antigen DRB1*1
P03437 HEMA_I68A0 Influenza A virus (A/Aichi/2/1968(H3N2)) Hemagglutinin