PDB Information

PDB3RLY
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Ligand binding stepwise disrupts water network in thrombin: enthalpic and entropic changes reveal classical hydrophobic effect
Biela, A., Sielaff, F., Terwesten, F., Heine, A., Steinmetzer, T., Klebe, G.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-04-20
Resolution1.510
CATH Insert Date27 May, 2012

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 28 May, 2012 Chopped
I 28 May, 2012 Rejected
L 28 May, 2012 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3rlyH01 08 Jun, 2012 2.40.10.10 Assigned
3rlyH02 08 Jun, 2012 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P09945 HIRV2_HIRME Hirudo medicinalis Hirudin variant-2
P00734 THRB_HUMAN Homo sapiens Prothrombin