PDB 3pwy

PDB Information

PDB3PWY
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.
Erlanson, D.A., Arndt, J.W., Cancilla, M.T., Cao, K., Elling, R.A., English, N., Friedman, J., Hansen, S.K., Hession, C., Joseph, I., Kumaravel, G., Lee, W.C., Lind, K.E., McDowell, R.S., Miatkowski, K., Nguyen, C., Nguyen, T.B., Park, S., Pathan, N., Penny, D.M., Romanowski, M.J., Scott, D., Silvian, L., Simmons, R.L., Tangonan, B.T., Yang, W., Sun, L.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-12-09
Resolution3.500
CATH Insert Date24 Apr, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3pwyA01 03 May, 2011 3.30.200.20 Assigned
3pwyA02 03 May, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O15530 PDPK1_HUMAN Homo sapiens 3-phosphoinositide-dependent protein kinase 1