PDB Information

PDB3OXI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK.
Hom, R.K., Bowers, S., Sealy, J.M., Truong, A.P., Probst, G.D., Neitzel, M.L., Neitz, R.J., Fang, L., Brogley, L., Wu, J., Konradi, A.W., Sham, H.L., Toth, G., Pan, H., Yao, N., Artis, D.R., Quinn, K., Sauer, J.M., Powell, K., Ren, Z., Bard, F., Yednock, T.A., Griswold-Prenner, I.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-09-21
Resolution2.200
CATH Insert Date08 May, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 09 May, 2011 Chopped
J 09 May, 2011 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3oxiA01 15 May, 2011 3.30.200.20 Assigned
3oxiA02 15 May, 2011 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9UQF2 JIP1_HUMAN Homo sapiens C-Jun-amino-terminal kinase-interacting protein 1
P53779 MK10_HUMAN Homo sapiens Mitogen-activated protein kinase 10