PDB Information

PDB3N5E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase.
Cardinale, D., Guaitoli, G., Tondi, D., Luciani, R., Henrich, S., Salo-Ahen, O.M., Ferrari, S., Marverti, G., Guerrieri, D., Ligabue, A., Frassineti, C., Pozzi, C., Mangani, S., Fessas, D., Guerrini, R., Ponterini, G., Wade, R.C., Costi, M.P.
Proc.Natl.Acad.Sci.USA
HeaderTransferase/Transferase Inhibitor
Released2010-05-25
Resolution2.260
CATH Insert Date12 Jun, 2011

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 13 Jun, 2011 Chopped
B 13 Jun, 2011 Chopped
D 13 Jun, 2011 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3n5eA00 16 Jun, 2011 3.30.572.10 Assigned
3n5eB00 16 Jun, 2011 3.30.572.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase