PDB Information

PDB3I0S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHIV-1 M:B_HXB2R
Primary Citation
Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants.
Su, D.S., Lim, J.J., Tinney, E., Wan, B.L., Young, M.B., Anderson, K.D., Rudd, D., Munshi, V., Bahnck, C., Felock, P.J., Lu, M., Lai, M.T., Touch, S., Moyer, G., Distefano, D.J., Flynn, J.A., Liang, Y., Sanchez, R., Prasad, S., Yan, Y., Perlow-Poehnelt, R., Torrent, M., Miller, M., Vacca, J.P., Williams, T.M., Anthony, N.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-06-25
Resolution2.700
CATH Insert Date30 Aug, 2009

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 Aug, 2009 Chopped
B 30 Aug, 2009 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
3i0sA01 10 Mar, 2010 3.10.10.10 Assigned
3i0sA02 10 Mar, 2010 3.30.70.270 Assigned
3i0sA03 10 Mar, 2010 3.30.70.270 Assigned
3i0sA04 10 Mar, 2010 3.30.70.270 Assigned
3i0sA05 10 Mar, 2010 3.30.420.10 Assigned
3i0sB01 10 Mar, 2010 3.10.10.10 Assigned
3i0sB02 10 Mar, 2010 3.30.70.270 Assigned
3i0sB03 10 Mar, 2010 3.30.70.270 Assigned
3i0sB04 10 Mar, 2010 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein