PDB Information

PDB3EKK
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase.
Chamberlain, S.D., Wilson, J.W., Deanda, F., Patnaik, S., Redman, A.M., Yang, B., Shewchuk, L., Sabbatini, P., Leesnitzer, M.A., Groy, A., Atkins, C., Gerding, R., Hassell, A.M., Lei, H., Mook, R.A., Moorthy, G., Rowand, J.L., Stevens, K.L., Kumar, R., Shotwell, J.B.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2008-09-19
Resolution2.100
CATH Insert Date25 Dec, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Dec, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3ekkA01 01 Apr, 2009 3.30.200.20 Assigned
3ekkA02 01 Apr, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P06213 INSR_HUMAN Homo sapiens Insulin receptor