PDB Information

PDB3DT1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold.
Herberich, B., Cao, G.Q., Chakrabarti, P.P., Falsey, J.R., Pettus, L., Rzasa, R.M., Reed, A.B., Reichelt, A., Sham, K., Thaman, M., Wurz, R.P., Xu, S., Zhang, D., Hsieh, F., Lee, M.R., Syed, R., Li, V., Grosfeld, D., Plant, M.H., Henkle, B., Sherman, L., Middleton, S., Wong, L.M., Tasker, A.S.
J.Med.Chem.
HeaderTransferase
Released2008-07-14
Resolution2.8
CATH Insert Date16 Oct, 2008

PDB Images (4)

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Oct, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3dt1A01 17 Oct, 2008 3.30.200.20 Assigned
3dt1A02 17 Oct, 2008 1.10.510.10 Assigned

Uniprot Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Cytokine suppressive anti-inflammatory drug-binding protein