PDB Information

PDB2XCN
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHEPATITIS C VIRUS
Primary Citation
Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Li, Q., Zhou, Y., Plattner, J.J., Baker, S.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., White, G.V., Mordaunt, J.E., Lazarides, L.X., Slater, M.J., Jarvest, R.L., Edge, C.M., Hubbard, J.A., Nassau, P., Mcdowell, B., Skarzynski, T.J., Thommes, P., Ellis, M., Rowland, P., Somers, D.O., Kazmierski, W.M., Grimes, R.M., Wright, L.L., Smith, G.K., Zou, W., Wright, J., Pennicott, L.E.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2010-04-23
Resolution3.020
CATH Insert Date06 Jun, 2010

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 06 Jun, 2010 Chopped
B 06 Jun, 2010 Chopped
C 06 Jun, 2010 Rejected
D 06 Jun, 2010 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2xcnA01 09 Jun, 2010 2.40.10.120 Assigned
2xcnA02 09 Jun, 2010 2.40.10.10 Assigned
2xcnB01 09 Jun, 2010 2.40.10.120 Assigned
2xcnB02 09 Jun, 2010 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q91RS4 Q91RS4_9HEPC Hepatitis C virus NS3 protease
Q91RS4 Q91RS4_9HEPC Hepatitis C virus NS3 protease